Harmful Interactions National Institute on Alcohol Abuse and Alcoholism NIAAA

acetaminophen and alcohol

Together, acetaminophen and alcohol can irritate the stomach and, in severe cases, cause ulcers, internal bleeding, and liver damage. Some over the counter painkillers combine many different types of pain relieving agents. For example, Excedrin combines aspirin and ibuprofen, while Excedrin Migraine combines asprin and caffeine. Combo pills are super dangerous with alcohol because you’re risking the side effects of several different types of pain relievers.

Why Medications and Alcohol Don’t Mix

Even moderate alcohol What Are Shrooms And Other Magic Mushroom FAQs consumption can heighten the susceptibility to acetaminophen-induced liver injury. These medications are controlled substances, require a prescription, can be habit-forming and lead to serious injury or death if not used properly. Opioid painkillers, when mixed with alcohol can lead to life-threatening interactions, such as slowing or stopping breathing. Always read the label and package insert of any medication you are taking, whether it has been prescribed by your doctor or purchased over-the-counter.

While it typically gets better after stopping taking the medications, there has been concern that alcohol (which is metabolized by the liver) could potentially make liver inflammation worse. Certain types of anti-nausea medication can be used to help someone who is trying to stop drinking alcohol. When used under medical supervision, the combination can be an effective way to treat alcohol withdrawal. You should avoid drinking alcohol if you are taking allergy medications or any multi-symptom cold and flu formulation. Medications used to treat insomnia or help you fall and stay asleep should never be mixed with alcohol. The sedating effect of these drugs can be increased by alcohol, leading to slowed or impaired breathing, impaired motor control, abnormal behavior, memory loss, and fainting.

  1. Mixing these medications with alcohol intensifies the side effects and increases the risk of a fatal overdose.
  2. The two have very similar side effects so by taking both at the same time, you’re increasing your chances of experiencing drowsiness, grogginess and an inability to safely operate some machinery.
  3. Alcohol and acetaminophen — the active ingredient of Tylenol — can negatively affect the liver when taken independently.
  4. As long as you are not taking medications that interact with alcohol, probably not.

Health Products

If you drink alcohol, it’s important to keep this in mind so you can avoid accidentally combining them. Heavy drinking for males is defined as having five or more alcoholic drinks on any one day or 15 or more in a week. Small amounts of Tylenol can stay in the body for up to 24 hours after a dose. Consider separating Tylenol and alcohol by a full day for optimal safety. Tens of thousands of people become ill every year from taking too much acetaminophen.

Narcotic Analgesic Interactions with Alcohol

acetaminophen and alcohol

However, the exact amounts of alcohol or Tylenol that can harm the liver aren’t clear. They mainly occur when people take acetaminophen alongside certain opioid drugs in an attempt to relieve pain. However, there is no scientific evidence that people with AUD who take the recommended dose of acetaminophen increase their risk of liver damage. For example, research suggests chronic alcohol consumption can worsen liver damage from acetaminophen overdose.

Blood Thinners

However, it may occur in people who take acetaminophen in excess or have certain underlying health conditions, especially ones affecting the liver. Tylenol (acetaminophen) is an over-the-counter medication for pain and reducing fevers. These medications all reduce prostaglandins, which cause pain and fever. When a woman drinks, the alcohol in her bloodstream typically reaches a higher level than a man’s even if both are drinking the same amount. This is because women’s bodies generally have less water than men’s bodies. Because alcohol mixes with body water, a given amount of alcohol is more concentrated in a woman’s body than in a man’s.

Taking these medicines with even one drink a day may cause bleeding in your digestive tract. OTC Tylenol labels specify that liver damage may occur if an adult takes Tylenol with three or more alcoholic drinks. However, at high doses and with prolonged use, it can seriously damage the liver and is a leading cause of acute (sudden) liver failure. If you ever have concerns about how much acetaminophen you can tolerate based on your age, body size, and health status, talk to your doctor or pharmacist. Here are some general precautions for avoiding an accidental overdose of acetaminophen.